Postdoc Computational Immunology

About your role

You will develop a mechanistic multiscale model of the lymph node, with a focus on understanding adaptive immune responses. You will work closely with principal investigators and fellow researchers at Amsterdam UMC and other institutes. You will also present and discuss your results in team meetings.

Your tasks include:

• Developing an initial model in the Julia programming language, focusing on T-cell activation at the cellular and molecular level, including cell motility and cell-cell interactions, gene regulatory and signalling networks, and chemokine gradients.
• Extending the model to include additional lymph node compartments or processes, such as the B-cell region and germinal centre dynamics, or stromal and fibroblast populations.
• Using single-cell omics and other datasets from public repositories and collaborators to define and parameterize the model.
• Ensuring that the model is well documented and accessible to other researchers by using our ENCORE framework.
• Contributing to teaching at Amsterdam UMC or the University of Amsterdam and writing a grant proposal to attract research funding and establish your own research line.
  About you
  You are a computational scientist with a strong interest in biology, immunology and single-cell omics. You combine technical expertise with analytical thinking and clear communication. You are an ambitious researcher who enjoys working in an interdisciplinary environment and taking the lead in developing a research project.You bring:
• A PhD in computational science or a related field and experience in a previous postdoctoral research position.
• Experience with agent-based modelling and differential equations.
• Strong programming skills in Julia or Python and experience with tools such as Git, Visual Studio Code and CoPilot or Claude Code.
• Strong communication, presentation and scientific writing skills, with the ability to work independently and collaboratively.
• A good command of English, both spoken and written.Knowledge or experience with R, immunology and single-cell omics is an advantage.
  Our offer
  
• You will be employed by Amsterdam UMC Research BV.
• A contract for 12 months, with the intention to extend for a total of two years.
• Classification in salary scale 10: € 3.724 to € 5.867 gross for full-time employment (depending on experience). In addition to a good basic salary, we offer 8.3% end-of-year bonus. Calculate your net salary here.
• Holiday hours: 194.4 per year for full time and a possibility to save additional hours.
• 100% reimbursement for public transport travel costs. If you travel by foot, bicycle, or car, a mileage allowance of €0.21 per km applies (up to a maximum of 40 km one way by car).
• Do you prefer walking or cycling? Take advantage of our good bike scheme.
• Pension accrual with BeFrank, a modern, comprehensible and fairly priced pension.Watch this video with more information about joining Amsterdam UMC Research BV.