Karlsruhe Institute of Technology 
Eggenstein-Leopoldshafen, Germany Résumé de l'offre
The Karlsruhe Institute of Technology invites a part‑time Academic Researcher (f/m/d) to join the Institut für Biologische Grenzflächen 4 – Magnetische Resonanz (IBG 4) in Eggenstein‑Leopoldshafen, Germany. The role focuses on metabolomics of medaka fish using nuclear magnetic resonance (NMR) spectroscopy, coupled with RNA‑seq and behavioral phenotyping. Responsibilities include NMR analysis, swim‑tunnel experiments, tissue extraction, statistical and correlation analyses, and equipment maintenance. Candidates should hold a Master’s or equivalent in chemistry, biology or a related field, possess analytical and statistical expertise, and be fluent in English. The annual gross salary ranges from €37,500 to €42,200.
Généré à partir du contenu enregistré de l'offre. Vérifiez toujours les détails dans l'annonce officielle.
Description du projet
The research at IBG-4 focuses on scientific objectives that can be addressed using nuclear magnetic resonance. The Muhle-Goll Laboratory applies NMR spectroscopy to biological and medical questions and has extensive experience in metabolomic analysis.
As part of the project, complex traits and their potential interactions in medaka fish are being investigated. Eighty nearly homozygous fish lines are being phenotyped for their voluntary swimming activity and analyzed using RNA sequencing and NMR metabolomic fingerprinting. RNA sequencing of various tissues will be performed to identify metabolic differences, and behavioral phenotyping will be conducted using open-field and swim-tunnel tests. The extracts from the respective tissues will be examined for characteristic differences using NMR spectroscopy and statistically evaluated.
Your tasks
- Metabolomics studies on medaka fish lines using NMR spectroscopy
- Swim-tunnel experiments and organ dissection followed by tissue extraction
- Analysis of the extracts using NMR spectroscopy
- Uni- and multivariate statistical analysis
- Correlation analysis with genome and RNA-Seq data
- Maintenance of computer and laboratory equipment, particularly the spectrometers
- Assistance with general computer and laboratory organization, as well as procurement and disposal
Your profile
- A completed university degree (Master’s/Diploma) in chemistry, biology, or a related field
- Experience with analytical techniques
- Comprehensive knowledge of statistics
- Good written and spoken English skills
Please submit a cover letter, a resume, a motivation letter and a letter of recommendation.
