Garvan Institute of Medical Research 
Sydney, Australia Offer Summary
The Garvan Institute of Medical Research in Sydney, Australia, is seeking a PhD Candidate for the Immunogenomics of Arthritic Joint Disease project. This full-time position spans 3.5 years with an annual stipend of $39,991 and a one-off $25,000 Global Mobility Grant. The role involves applying genomic technologies at the Broad Institute of MIT and Harvard to analyze unique single-cell datasets from arthritic joints. Candidates must be domestic applicants. Applications require a CV, transcripts, and a detailed cover letter, closing on November 11th. This research aims to uncover disease mechanisms and novel drug targets for arthritis, addressing significant health challenges in Australia.
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Project Description
Immunogenomics of Arthritic Joint Disease
Our top PhD candidate will travel between the Garvan Institute, and Broad Institute of MIT and Harvard, in Cambridge.
You will apply genomic technologies and analytical pipelines uniquely available at Broad, to the fastest growing Arthritis Tissue Biobank in Australia, within Garvan’s Masle-Farquhar Lab.
Arthritis affects 3.7 million Australians, causing ongoing pain, disability, isolation, comorbidities and premature deaths. Treatments are trial-and-error; only ~20% of rheumatoid or psoriatic arthritis patients reach remission. Osteoarthritis has no approved disease-modifying drug.
You will analyse the world's first single-cell, long-read sequencing dataset integrating transcriptome, clonotypes, isoforms and acquired mutations – directly within diseased arthritic joints. And access other unique datasets, including large-scale single-cell genetics analyses of hundreds of patients.
Your insights into disease mechanisms, treatment resistance, and novel drug targets will directly feed our established pipeline for producing and pre-clinically testing novel arthritis therapies.
Scholarship value
$39,991 per annum (2027 rate) stipend for 3.5 years
$25,000 Global Mobility Grant (one-off)
Candidates must be domestic. Applications close 11th of November. We will review applications as soon as they arrive.
Applications must include CV, transcripts, and thoughtful, detailed and original cover letter.
Academic Contact
Contact details were not provided by the official source.
