Offer Summary
The University of Bern invites applications for a full-time PhD Student position in Cancer Immunology and Leukemia Stem Cell Biology within the Department for BioMedical Research. Starting January 1, 2027, or by arrangement, this four-year fixed-term role focuses on investigating molecular interactions between leukemia stem cells and immune cells in acute myeloid leukemia. Responsibilities include conducting flow cytometry, cell sorting, and multi-omics analyses using patient samples and mouse models to identify novel immunotherapeutic targets. Candidates require an MSc in biological sciences or related fields, with experience in cell culture and RT-qPCR. Advantages include transcriptomics and R skills. The position offers a salary according to SNF regulations, access to strong research infrastructure, and a collaborative environment in central Bern. Applicants should submit their motivation letter, CV, transcripts, and referee contacts via email.
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Project Description
PhD Student in Cancer Immunology and Leukemia Stem Cell Biology
Start Date 01.01.2027 or by arrangement
Employment Relationship 100%, fixed-term, 4 years
Institution / Workplace Tumor Immunology Department for BioMedical Research (DBMR) University of Bern and Inselspital Bern Bern
Project description
- Investigation of molecular and cellular interactions between leukemia stem cells (LSCs) and immune cells, with a particular focus on acute myeloid leukemia (AML).
- We aim to understand how these interactions influence leukemia progression, immune responses, and therapeutic resistance.
- Our research combines molecular biology, immunology, multi-omics approaches including primary patient samples, and preclinical mouse models to identify potential targets for novel immunotherapeutic strategies.
Your responsibilities
- Investigate interactions of LSCs with NK cells and B cells.
- Perform flow cytometry, cell sorting, co-culture and functional assays.
- Analyze transcriptomic and multi-omics data.
- Validate findings in vitro and in preclinical mouse models.
- Present results and contribute to publications.
For more information about our research, please see our recent publications (PMIDs: 38941612, 37643244, 30877275).
Your profile
- MSc in biological sciences, immunology, molecular biology, medicine or related field.
- Experience with cell culture, RT-qPCR and flow cytometry.
- Transcriptomics, R and mouse-model experience are advantages.
- Good English communication skills.
- Scientific curiosity, analytical thinking, and the ability to work independently and collaboratively.
Your Benefits
- Salary according to SNF regulations, technologies, patient samples
- Strong research infrastructure and international network
- Collaborative environment and ambitious team
- Central location in the heart of Bern
Working at the University of Bern
The University of Bern not only offers exciting tasks but also an environment that actively promotes development, diversity, and equal opportunities. Discover what makes us stand out as an employer and how you can grow with us.
Application and Contact
Please email a motivation letter, CV, academic transcripts and contact details of two referees (preferably as one PDF) to ramin.radpour@unibe.ch
Questions about the position?
Tumorimmunology
PD Dr. Ramin Radpour ramin.radpour@unibe.ch
Questions about the application?
PD Dr. Ramin Radpour
ramin.radpour@unibe.ch
University of Bern
Bern, Switzerland