University College London 
London, United Kingdom Descrição do projeto
About us
The mission of the UCL GOS Institute of Child Health is to maximise and advocate for the holistic health of all children, young people and the adults they will become, through world-class research, education and public engagement. The UCL GOS ICH, together with its clinical partner Great Ormond Street Hospital for Children, forms the largest concentration of children’s health research outside North America. The 2024-29 GOS ICH strategy focuses on its five scientific programmes. GOS ICH’s activities include active engagement with children and families, to ensure that our work is relevant and appropriate to their needs. GOS ICH generates the funding for our research by setting out our proposals in high quality applications to public, charitable and industrial funding bodies and disseminates the results of our research by publication in the medical and scientific literature, to clinicians, policy makers and the wider public. The Institute offers world-class education and training across a wide range of teaching and life learning programmes which address the needs of students and professional groups who are interested in and undertaking work relevant to child health. GOS ICH holds an Athena SWAN Charter Gold Award.
About the role
Take part in a research project aiming to develop a gene therapeutic approach for the progressive childhood-onset neurodegenerative disorder Beta Propeller Protein-Associated Neurodegeneration (BPAN), using human induced pluripotent stem cells (iPSCs)-derived organoids models. This post is available from 15/01/2027 until 31/12/2027, in the first instance.
About you
The successful candidate will be involved in modeling Propeller Protein-Associated Neurodegeneration (BPAN) using human induced pluripotent stem cells (iPSCs)-derived organoids models. Models will be use to test gene therapy. Specifically, the successful candidate will be involved in: Maintenance of iPSCs and differentiation of brain organoids models, generate viral vectors for gene therapy, evaluate the efficacy of gene therapy in the organoid model, general maintenance of good operating laboratory. PhD in biological sciences or submitted PhD thesis in biological sciences is essential.
What we offer
As well as the exciting opportunities this role presents, we also offer some great benefits some of which are below: • 41 Days holiday (27 days annual leave 8 bank holiday and 6 closure days) • Additional 5 days’ annual leave purchase scheme • Defined benefit career average revalued earnings pension scheme (CARE) • Cycle to work scheme and season ticket loan • Immigration loan • Relocation scheme for certain posts • On-Site nursery • On-site gym • Enhanced maternity, paternity and adoption pay • Employee assistance programme: Staff Support Service • Discounted medical insurance Visit Reward and benefits to find out more.
Our commitment to Equality, Diversity and Inclusion
As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women. You can read more about our commitment to Equality, Diversity and Inclusion here : Equality diversity inclusion If you have any queries regarding the application process, please contact Madhur Sharma on ich.hr@ucl.ac.uk quoting job reference